– Hippocrates
Make yourself periodic preventive laboratory tests every six months. Thus you will benefit a huge advantage - namely, enough time to react in the management of a disease in its early stages, before the wandering panic at the last moment.
Here's what you should lab test:
• CBC (Complete Blood Count) + DBC (Differential Blood Count)
• ESR (Erythrocyte Sedimentation Rate)
• Blood sugar
• Prothrombin time (INR)
• Folic acid (B9)
• Vitamin B12
• Homocysteine
• Alkaline phosphatase (APL)
• Lactate Dehydrogenase (LDH)
• C-reactive protein
• Cholesterol (lipid) profile – complex test
• Rheumatoid factor
• Hepatic enzymes – complex test
• K, Na, Cl (potassium, sodium, chloride)
• Ca (calcium)
• P (phosphorus)
• Mg (magnesium)
• Fe (iron)
• Renal function – complex test
• Uric acid
Remark:
The complex tests included in the above list contain in themselves the following elements:
• Renal function
- Uric acid
- Sediment
- pH of urine
- Total protein
- albumin
- creatinine
- blood
• Cholesterol (lipid) profile:
- Total cholesterol
- Triglycerides
- HDL (High Density Lipoproteins - "good")
- LDL (low density lipoproteins - "bad")
• Hepatic enzymes:
- AST (Aspartate Aminotransferase)
- ALT (Alanine Aminotransferase)
- Gamma GT (Gamma-Glutamyl Transpeptidase)
- Bilirubin
• Renal function
- Uric acid
- Sediment
- pH of urine
- Total protein
- albumin
- creatinine
- blood
• Cholesterol (lipid) profile:
- Total cholesterol
- Triglycerides
- HDL (High Density Lipoproteins - "good")
- LDL (low density lipoproteins - "bad")
• Hepatic enzymes:
- AST (Aspartate Aminotransferase)
- ALT (Alanine Aminotransferase)
- Gamma GT (Gamma-Glutamyl Transpeptidase)
- Bilirubin
However, before you start to analyse any data from laboratory tests have in mind that a mass phenomenon in private and state laboratories, private clinics and university hospitals is the replacement of the physiologically normal reference ranges with those that are not only misleading but also criminally false. Why is this happening to this day I do not want to comment although the explanation is easy to guess. To avoid this "inconvenience" I attached herein below a list of reference values and ranges of most of the important medical lab test that have been checked from me in the textbooks of physiology and biochemistry.
Reference values are for adults:
1. BLOOD
|
|||
1.1 BLOOD CELL
COUNT
|
|||
Erythrocytes
|
men
|
4.4 – 5.9
|
1012/l
|
women
|
3.7 – 5.3
|
1012/l
|
|
Hemoglobin
|
men
|
135 – 180
|
g/l
|
women
|
120 – 160
|
g/l
|
|
Hemoglobin fractions
|
|||
-
Hb A
|
92 – 96
|
%
|
|
-
Hb A2
|
2 – 3
|
%
|
|
-
Hb F
|
0.3 – 1.0
|
%
|
|
Glycated HbA1c
|
up to 6.4
|
%
|
|
Hematocrit
|
men
|
0.40 – 0.53
|
|
women
|
0.36 – 0.48
|
||
MCV (Mean Corpuscular Volume)
|
82 – 96
|
fl
|
|
MCH (Mean Corpuscular Hemoglobin)
|
27 – 33
|
pg
|
|
MCHC (Mean Corpuscular Hemoglobin Concentration)
|
300 – 360
|
g/l
|
|
Reticulocytes
|
0.002 – 0.018
|
(24-48 x 109/l)
|
|
Leukocytes
|
3.5 – 10.5
|
109/l
|
|
Leukogram
|
|||
- Neutrophils (St, Sg):
|
|||
St (stabs)
|
0.00 – 0.06
|
(0.00 – 0.50 x 109/l)
|
|
Sg (segs)
|
0.40 – 0.70
|
(2.10 – 6.40 x 109/l)
|
|
- Eo
(eosinophils)
|
0.00 – 0.06
|
(0.00 – 0.50 x 109/l)
|
|
- Ba (basophils)
|
0.00 – 0.02
|
(0.00 – 0.14 x 109/l)
|
|
- Mo (monocytes)
|
0.01 – 0.11
|
(0.07 – 0.80 x 109/l)
|
|
- Ly
(lymphocytes)
|
0.20 – 0.48
|
(1.10 – 3.80 x 109/l)
|
|
Platelets
|
130 – 360
|
109/l
|
|
ESR (Erythrocyte Sedimentation Rate)
|
men up to 50's
|
up to 18
|
mm/h
|
men over 50's
|
up to 22
|
mm/h
|
|
women up to 50's
|
up to 25
|
mm/h
|
|
women over 50's
|
up to 30
|
mm/h
|
|
1.2 BLOOD
COAGULATION
|
|||
Bleeding time
|
2 – 5
|
min
|
|
Prothrombin time (PT):
|
10 – 15
|
s
|
|
activity
|
70 – 120
|
%
|
|
ratio (INR)
|
0.9 – 1.15
|
||
aPTT
|
25 – 38
|
s
|
|
Thrombin time
|
18 – 23
|
s
|
|
ratio (INR)
|
0.85 – 1.15
|
||
Fibrinogen
|
2 – 4
|
g/l
|
|
Therapeutic area:
|
|||
Prothrombin time (PT):
|
|||
activity
|
30 – 15
|
%
|
|
ratio (R)
|
2 – 3 (4)
|
||
INR
|
2.0 – 4.0
|
||
aPTT ratio
|
1.5 – 2.5
|
||
D-dimer
|
up to 0.2
|
µg/ml
|
|
Coagulation factors
|
50 – 150
|
%
|
|
Antithrombin (AT)
|
80 – 120
|
%
|
|
Protein C (Pr C)
|
70 – 140
|
%
|
|
Protein S (Pr S)
|
70 – 140
|
%
|
|
Plasminogen (PI)
|
80 – 120
|
%
|
|
α2-antitrypsin
|
80 – 120
|
%
|
|
Platelet aggregation
|
over 60
|
%
|
|
1.3
ELECTROLYTES AND OLIGOELEMENTS
|
|||
S-Osmolality
|
280 – 295
|
mosm/l
|
|
S-K (potassium)
|
3.5 – 5.6
|
mmol/l
|
|
S-Na (sodium)
|
136 – 151
|
mmol/l
|
|
S-Cl (chloride)
|
96 – 110
|
mmol/l
|
|
S-Ca (calcium)
|
2.12 – 2.62
|
mmol/l
|
|
S-iCa2+ (calcium ions)
|
adults
|
1.1 – 1.3
|
mmol/l
|
children
|
1.1 – 1.5
|
mmol/l
|
|
S-P (phosphorous)
|
adults
|
0.84 – 1.45
|
mmol/l
|
children
|
0.95 – 1.95
|
mmol/l
|
|
S-Fe (iron, ferrozine, ferrum)
|
men
|
12.5 – 26.7
|
µmol/l
|
women
|
10.7 – 23.4
|
µmol/l
|
|
(AAS)
|
men
|
10.2 – 36.4
|
µmol/l
|
women
|
9.2 – 33.9
|
µmol/l
|
|
S-JAC (Iron Binding Capacity)
|
44.8 – 71.6
|
µmol/l
|
|
S-Cu (copper)
|
men
|
12.3 – 22.4
|
µmol/l
|
women
|
13.2 – 24.3
|
µmol/l
|
|
S-Zn (zinc)
|
12 – 24
|
µmol/l
|
|
S-Mg (magnesium)
|
0.7 – 1.2
|
mmol/l
|
|
S-iMg2+ (magnesium ions)
|
0.33 – 0.57
|
mmol/l
|
|
B-Pb (lead)
|
8 – 269
|
µg/l
|
|
S-Li (lithium)
|
0.86 – 4.5
|
µmol/l
|
|
S-Se (selenium)
|
423 – 1123
|
nmol/l
|
|
S-Cd (cadmium)
|
1.0
|
µg/l
|
|
smokers
|
2.0
|
µg/l
|
|
S-Al (aluminium)
|
0 – 10
|
µg/l
|
|
S-Mn (manganese)
|
0.5 – 0.7
|
µg/l
|
|
B-Mn (manganese)
|
4 – 14
|
µg/l
|
|
S-As (arsenic)
|
0.5 – 1.5
|
µg/l
|
|
B-As (arsenic)
|
2 – 7
|
µg/l
|
|
B-Mo (molybdenum)
|
0.8 – 3.3
|
µg/l
|
|
B-Ni (nickel)
|
4.5 – 28
|
µg/l
|
|
B-Cr (chromium)
|
2.8 – 45
|
µg/l
|
|
S-Cr (chromium)
|
0.12 – 2.1
|
µg/l
|
|
1.4 SUBSTRATES
|
|||
S-Bilirubin
|
Total
|
3.4 – 21
|
µmol/l
|
direct
|
0.8 – 8.5
|
µmol/l
|
|
S-Glucose
|
venous blood
|
2.8 – 6.1
|
mmol/l
|
S-Glucose
|
capillary blood
|
3.5 – 5.5
|
mmol/l
|
S-Creatinine
|
men
|
74 – 127
|
µmol/l
|
women
|
58 – 96
|
µmol/l
|
|
S-Uric acid
|
men
|
214 – 488
|
µmol/l
|
women
|
137 – 363
|
µmol/l
|
|
S-Urea
|
men
|
3.2 – 9.2
|
mmol/l
|
women
|
2.6 – 7.2
|
mmol/l
|
|
S-Homocysteine
|
4.7 – 13.8
|
µmol/l
|
|
P-Ammonia
|
10 – 47
|
µmol/l
|
|
P-Lactate
|
0.6 – 1.5
|
mmol/l
|
|
1.5 LIPID
STATUS
|
|||
S-Cholesterol
|
3.4 – 5.2
|
mmol/l
|
|
S-HDL ( "good" cholesterol)
|
men
|
above 0.9
|
mmol/l
|
women
|
above 1
|
mmol/l
|
|
S-LDL ( "bad" cholesterol)
|
2.6 – 3.2
|
mmol/l
|
|
S-VLDL
|
up to 0.9
|
mmol/l
|
|
Cholesterol / HDL ratio
|
up to 5
|
mmol/l
|
|
S-Triglycerides
|
0.6 – 1.7
|
mmol/l
|
|
1.6 ENZYMES
|
|||
S-AST (ASAT)
|
5 – 40
|
U/L
|
|
S-ALT (ALAT)
|
5 – 40
|
U/L
|
|
S-CK (Creatine Kinase)
|
men
|
30 – 200
|
U/L
|
women
|
20 – 180
|
U/L
|
|
S-γGT
|
men
|
< 50
|
U/L
|
women
|
< 35
|
U/L
|
|
S-ALP (alkaline phosphatase)
|
< 280
|
U/L
|
|
S-LDH (lactate dehydrogenase)
|
230 – 460
|
U/L
|
|
S-HBD (hydroxybutyrate dehydrogenase)
|
< 200
|
U/L
|
|
S-Cholinesterase
|
5300 – 12900
|
U/L
|
|
S-Leucine Amino Peptidase
|
8 – 22
|
U/L
|
|
S-α-Amylase
|
< 95
|
U/L
|
|
S-AP (acid phosphatase)
|
men
|
up to 6.5
|
U/L
|
women
|
up to 5.5
|
U/L
|
|
Prostate
|
up to 2.6
|
U/L
|
|
S-Lipase
|
up to 195
|
U/L
|
|
1.7 PROTEINS
|
|||
S-Total protein
|
60 – 83
|
g/l
|
|
S-Albumin
|
35 – 53
|
g/l
|
|
Proteinogram
|
|||
-
S-Albumin
|
52 – 69
|
%
|
|
-
S-α1-globulin
|
1.6 – 4.1
|
%
|
|
-
S-α2-globulin
|
7.4 – 13
|
%
|
|
-
S-β-globulin
|
8 – 14.9
|
%
|
|
-
S-γ-globulin
|
10.5 – 20.5
|
%
|
|
S-α1-antitrypsin
|
0.9 – 2.0
|
g/l
|
|
S-α1-acid glycoprotein
|
0.5 – 1.2
|
g/l
|
|
S-α2-macroglobulin
|
0.7 – 4.0
|
g/l
|
|
S-C3
|
0.9 – 1.8
|
g/l
|
|
S-C4
|
0.1 – 0.4
|
g/l
|
|
S-ceruloplasmin
|
0.2 – 0.6
|
g/l
|
|
S-heptoglobin
|
0.3 – 2.0
|
g/l
|
|
S-prealbumin
|
0.2 – 0.4
|
g/l
|
|
S-transferrin
|
2.0 – 3.6
|
g/l
|
|
S-Ferritin
|
men
|
20 – 280
|
µg/l
|
women
|
10 – 140
|
µg/l
|
|
postmenopausal women
|
25 – 250
|
µg/l
|
|
S-Soluble Transferrin Receptor (sTfR)
|
0.83 – 1.76
|
mg/l
|
|
S-Cystatin C
|
0.50 – 0.96
|
mg/l
|
|
S-β2-microglobulin
|
0.96 – 2.08
|
mg/l
|
|
S-CRP
|
≤ 5
|
mg/l
|
|
S-β-lipoprotein
|
15 – 65
|
||
S-thymol test
|
up to 40
|
||
S-IgA
|
0.7 – 4.0
|
g/l
|
|
S-IgG
|
7.0 – 16.0
|
g/l
|
|
S-IgM
|
0.4 – 2.3
|
g/l
|
|
S-IgE
|
up to 100
|
IU/ml
|
|
S-light chain type κ
|
17 – 37
|
mg/l
|
|
S-light chain type λ
|
9 – 21
|
mg/l
|
|
S-κ/ λ
|
1.35 – 2.65
|
||
S-λ/κ
|
0.75 – 4.5
|
||
S-амилоид А (SAA)
|
< 6.4
|
mg/l
|
|
1.8 CONNECTIVE
TISSUE MARKERS
|
|||
S-Osteocalcin
|
men
|
3.4 – 9.1
|
ng/ml
|
women
|
3.7 – 10
|
ng/ml
|
|
S-C-terminal propeptide of
|
|||
collagen I
|
men
|
76 – 163
|
ng/ml
|
women
|
69 - 147
|
ng/ml
|
|
1.9 HORMONES
|
|||
S-FT3
|
3.54 – 6.47
|
pmol/l
|
|
S-FT4
|
11.5 – 23.2
|
pmol/l
|
|
S-TSH
|
0.35 – 5.5
|
mlU/l
|
|
S-Cortisol
|
8:00 hours
|
118.2 – 618
|
nmol/l
|
17:00 hours
|
85.3 – 459.6
|
nmol/l
|
|
S-Prolactin
|
men
|
44.5 – 375.2
|
mlU/l
|
women
|
59.3 – 619.0
|
mlU/l
|
|
S-PTH
|
1.59 – 6.89
|
pmol/l
|
|
S-IRI
|
3.00 – 28.00
|
mU/l
|
|
S-C-Peptid
|
0.26 – 0.66
|
nmol/l
|
|
S-DHEA-S
|
0.003 – 27.11
|
µmol/l
|
|
S-ATG
|
0.0 – 115.0
|
mU/l
|
|
S-ATPO
|
0 – 34
|
mU/l
|
|
S-Testosterone
|
men
|
8.36 – 28.7
|
nmol/l
|
women
|
0.49 – 2.64
|
nmol/l
|
Hormone
Follicular phase
|
LH
U/I
|
FSH
U/I
|
Estradiol
pmol/l
|
Progesterone
nmol/l
|
1.9 – 12.5
|
2.5 – 10.2
|
231 - 606
|
0.48 - 4.45
|
|
Ovulatory phase
|
8.7 – 76.3 (peak)
|
3.4 – 33.4 (peak)
|
536 – 1930
(peak)
|
-
|
Luteal phase
|
0.5 – 16.9
|
1.5 – 9.1
|
132.0 – 488.0
|
10.63 – 88.30
|
Menopause
|
15.9 – 54
|
23.0 – 116.3
|
0.0 – 136.0
|
0.0 – 2.32
|
Men (20-72)
|
1.5 – 9.3
|
1.4 – 18.1
|
0.0 – 191.0
|
0.89 – 3.88
|
1.10 VITAMINS
|
|||
S-Vit. В12 (total)
|
|
156 - 672
|
pmol/l
|
S-Vit. B12 active, holotranscobalamin
|
|
25.1 - 165
|
pmol/l
|
S-Vit. B9 (folic acid)
|
|
2.5 – 45.4
|
nmol/l
|
1.11 DRUGS
|
|||
S-Amikacin
|
peak value
|
20 – 30
|
mg/l
|
|
base value
|
< 8
|
mg/l
|
S-Valproic acid
|
|
350 – 700
|
µmol/l
|
S-Vancomycin
|
peak value
|
25 – 40
|
mg/l
|
|
base value
|
< 8
|
mg/l
|
S-Gentamicin
|
peak value
|
5 – 12
|
mg/l
|
|
base value
|
up to 2
|
mg/l
|
S-Digoxin
|
|
1 – 3
|
nmol/l
|
S-Diphenylhydantoin
|
|
40 – 80
|
µmol/l
|
S-Ethosuximide
|
|
280 – 700
|
µmol/l
|
S-Carbamazepine
|
|
17 – 51
|
µmol/l
|
S-Caffeine
|
|
40 – 70
|
µmol/l
|
S-Lamotrigine
|
|
5 – 15
|
mg/l
|
S-Monohydroxy Carbamazepine
|
|
8 – 40
|
mg/l
|
S-Primidone
|
|
23 -55
|
µmol/l
|
S-Theophylline
|
|
55 – 110
|
µmol/l
|
S-Phenobarbital
|
|
65 – 170
|
µmol/l
|
S-Chloramphenicol
|
peak value
|
30 – 60
|
µmol/l
|
B-Surolimus
|
|
5 – 24
|
µg/l
|
B-Tacrolimus
|
|
5 – 18
|
µg/l
|
B-Cyclosporine
|
|
100 – 250
|
µg/l
|
B-Cyclosporine C2
|
|
600 – 1700
|
µg/l
|
1.12 TUMOR
MARKERS
|
|||
S-CEA
|
|
0.0 – 4.6
|
µg/l
|
S-CA 125
|
|
up to 35.0
|
kU/l
|
S-CA – 15-3
|
|
up to 38.6
|
kU/l
|
S-CA – 19-9
|
|
up to 37.0
|
kU/l
|
S-PSA
|
|
0.0 – 4.0
|
µg/l
|
S-AFP
|
|
0.0 – 5.8
|
kU/l
|
1.13 CARDIAC
MARKERS
|
|||
S-Troponin I
|
|
0.0 – 1.5
|
µg/l
|
S-Troponin T
|
|
0.0
100.0
|
µg/l
|
S-Myoglobin
|
|
0.1 – 110.0
|
µg/l
|
1.14 ACID-BASE
BALANCE
|
|||
Ba-pH 37OC
|
|
7.36 – 7.44
|
-log mol
|
B-pCO2
|
|
4.66 – 5.99
|
kPa
|
B-SB
|
|
21 – 25
|
mmol/l
|
B-BE
|
|
-2.5 – 2.5
|
mmol/l
|
B-pO2
|
|
10.66 – 13.33
|
kPa
|
B-O2SAT
|
|
94 – 98
|
%
|
B-Lactate
|
|
0.5 – 2.2
|
mmol/l
|
2. URINE
|
|||
2.1
ELECTROLYTES AND OLIGOELEMENTS
|
|||
U-K (potassium)
|
|
25 – 125
|
mmol/24h
|
U-Na (sodium)
|
|
40 – 220
|
mmol/24h
|
U-Cl (chlorides)
|
|
110 – 250
|
mmol/24h
|
U-Ca (calcium)
|
|
2.5 – 7.5
|
mmol/24h
|
U-P (phosphorous)
|
|
10.9 – 32.3
|
mmol/24h
|
U-Cu (copper)
|
|
0.44 – 1.1
|
µmol/24h
|
U-Zn (zinc)
|
|
4.5 – 9.0
|
µmol/24h
|
U-Mg (magnesium)
|
|
7.1 – 11.7
|
mmol/24h
|
U-Pb (lead)
|
|
6.3 – 13.0
|
µg/l
|
Ca [mmol/l]/Creat [mmol/l]
|
|
< 0.57
|
|
U-Cd (cadmium)
|
|
0.5 – 4.7
|
µg/l
|
U-Mn (manganese)
|
|
20
|
µg/l
|
U-As (arsenic)
|
|
10 – 30
|
µg/l
|
U-Co (cobalt)
|
|
1.20 – 1.35
|
µg/l
|
U-Mo (molybdenum)
|
|
33 – 34
|
µg/l
|
U-Ni (nickel)
|
|
2.2 – 2.7
|
µg/l
|
U-Cr (chromium)
|
|
0.24 – 1.8
|
µg/l
|
U-osmolality
|
|
50 – 1400
|
mosm/kg H2O
|
2.2 SUBSTRATES
|
|||
U-Total protein
|
|
up to 150
|
mg/24h
|
U-Albumin
|
|
up to 30
|
mg/24h
|
U-Glucose
|
|
up to 0.83
|
mmol/24h
|
U-Creatinine
|
men
|
8800 – 17600
|
µmol/24h
|
|
women
|
5300 – 13200
|
µmol/24h
|
U-Uric acid
|
|
1190 – 4160
|
µmol/24h
|
U-Uric acid
|
men
|
200 – 420
|
µmol/l
|
|
women
|
140 – 340
|
µmol/l
|
U-α1-microglobulin
|
|
0 – 12
|
mg/l
|
U-albumin
(first urine in the morning)
|
|
< 20
|
mg/l
|
U-transferrin
(first urine in the morning)
|
|
< 2.5
|
mg/l
|
U-IgG
(first urine in the morning)
|
|
< 10
|
mg/l
|
2.3 ENZYMES
|
|||
U-α-amylase
|
|
< 450
|
U/L
|
2.4 CONNECTIVE
TISSUE MARKERS
|
|||
U-Deoxypiridin
|
men
|
2.3 – 5.4
|
nmol/mmol creat
|
|
women
|
3.0 – 7.4
|
nmol/mmol creat
|
2.5 HORMONES
|
|||
U-Free cortisol
|
|
93 – 320
|
nmol/24h
|
U-Adrenaline
|
|
0 – 81.9
|
nmol/24h
|
U-Noradrenaline
|
|
59 – 389
|
nmol/24h
|
U-5-Hydroxyindoleacetic acid
|
|
13.1 – 52.3
|
µmol/24h
|
2.6 ACID-BASE
BALANCE AND OTHER
|
|||
U-pH
|
|
4.5 – 8.2
|
|
U-Specific gravity (Density)
|
|
1.001 – 1.028
|
|
U-Sediment
|
|
4-5 Leukocytes, 2 Erythrocytes
|
|
3. FUNCTIONAL TESTS
|
|||
Creatinine clearance
|
|
1.33 – 3.00
|
ml/s/m2
|
Clearance of sodium
|
|
0.017
|
ml/s
|
Clearance of potassium
|
|
0.5
|
ml/s
|
4. CSF (cerebrospinal fluid)
|
|||
L-Protein
|
lumbar
|
0.15 – 0.45
|
g/l
|
|
ventricular
|
0.15 – 0.25
|
g/l
|
L-Glucose
|
|
2.22 – 4.44
|
mmol/l
|
L-sodium
|
|
138 - 153
|
mmol/l
|
Important!
Intake of a lot of medicines, vitamins and your particular health condition can significantly affect the results of laboratory tests, so be informed in advance for the technological requirements related to conducting of lab tested parameters. Any laboratory will advise you about them. For example vitamin C should be discontinued 3 days before each lab test, so as not to affect the results. The same is the situation with colds. In lab testing of ESR (sedimentation rate of erythrocytes) you should wait until full recovery from the illness in order to test this parameter. Excluding emergency cases, reliable data for most clinical laboratory indicators can be obtained if the biological fluids for their testing are taken in accordance with the biological (circadian) rhythms. As a rule, scheduled tests are conducted in the morning from 8:00 to 10:00 hours on an empty stomach, as on the previous day you must stop eating not later than 20:00 hours. Erroneous values in excess of 3 - 4 times the norm can be obtained especially when serum levels of many hormones and enzymes are tested if blood samples for their testing are taken at other times of the day.